Vetina KBR Tablet 500 mg

Description :

Bromides are used both as primary therapy and as adjunctive therapy to control seizures in dogs that are not adequately controlled by phenobarbital alone.

While historically bromides were only recommended for use alone in patients suffering from phenobarbital hepatotoxicity, bromides are more frequently used as a drug of first choice.


  • Seizures,
  • Anxiety


Each uncoated tablet contains:

Potassium bromide I.P.………500 mg

Cyanocobalamin I.P.……………10 mcg


Meat Flavoured


Bromide’s anti-seizure activity is thought to be the result of its generalized depressant effects on neuronal excitability and activity. Bromide ions compete with chloride transport across cell membranes resulting in membrane hyperpolarization, thereby raising seizure threshold and limiting the spread of epileptic discharges


VETINA KBR TM should not be used in animals with a history of hypersensitivity to Bromide or any of the components of the solution or tablet.


Dog may experience drowsiness when taking bromide, but this will generally go away after approximately 3 weeks. Increased hunger, thirst, urination, vomiting, constipation, anorexia, and uncoordinated movements may occur with bromide. During the load in dose increased nausea may be experienced


1×10 Tablets


Dosage :


Dosage and Frequency 

Half Life

Time to Steady State

Therapeutic level 

Adverse Effect / Comments

Bromide (potassium salt)

Dogs, cats: 20–40 mg/kg, PO, once daily or divided bid if GI upset. Caution using bromide in cats (see comments).

Dogs: loading dose 400–600 mg/kg, PO divided into 4 doses, given over 1–4 days


20–46 days

Cats: 10days

Horses: 5 days

Dogs: 100–200 days

Cats: 6 wk

Bromide alone: 1–3   mg/mL (15–20 μmol/L)

Bromide/phenobarbital combined: 1–2 mg/mL

Sedation,weakness, polydipsia, vomiting, polyphagia, skin rash. Reduce dose with renal insufficiency. High chloride intake increases bromide elimination. Chloride content of diet should be stable. Use with extreme caution in cats and monitor with thoracic radiographs because bronchial/asthmatic signs may be fatal in cats.

Vetina’s KBR  Tablet Dosing

To achieve a serum level of approximately 1 mg/mL, give 120 mg/kg PO daily for 5 days  Dose reduction to  30 mg/kg PO once daily.  For seizures:  400 – 600 mg/kg/day divided and given with food. May be given over 24 hours or more gradually over 5 days. Then go to initial maintenance dose: 20 – 30 mg/kg PO once daily
For Giving 120 mg /kg  daily : For Giving 30 mg /kg  daily : For Giving 500 mg /kg  daily :
Wt of Dog taken 10 Kgs  Wt of Dog taken 10 Kgs  Wt of Dog taken 10 Kgs 
Concentration of drug is 500 mg Concentration of drug is 500 mg  Concentration of drug is 500 mg
Dose Calculation  Dose Calculation  Dose Calculation 
120 mg X 10 kgs = 1200 mg (Dose requiremennt ) 30 mg X 10 kgs = 300 mg (Dose requiremennt ) 500 mg X 10 kgs = 5000 mg (Dose requiremennt )
1200/ 500 mg (Drug concentration ) 300/ 500 mg (Drug concentration ) 5000/ 500 mg (Drug concentration )
For 10 Kg Dog and Cat Dose = 2.5 tablet   For 10 Kg Dog and Cat Dose = 0.5 tablet For 10 Kg Dog and Cat Dose =10 tablet  
Dosing as per Weight per day for 5 days 

Dosing as per Weight

Dosing as per Weight for 5 days 

Weight  Dose  Weight  Dose  Weight  Dose 
5 kg  1.5 Tablet 5 kg  0.5 Tablet 5 kg  5 Tablet
10 kg 2.5 Tablet 10 kg 0.5 Tablet 10 kg 10 Tablet
15 kgs  3.5 Tablet 15 kgs  1 Tablet 15 kgs  15 Tablet
20 kgs  5 Tablets 20 kgs  1.5 Tablet 20 kgs  20 Tablets
25 kgs  6 Tablets 25 kgs  1.5 Tablet 25 kgs  25 Tablet
30 kgs  7.5 Tablet 30 kgs  2 Tablet 30 kgs  30 Tablet 
35 kgs  8.5 Tablet 35 kgs 2 Tablet 35 kgs  35 Tablet
40 kgs  9.5 Tablet 40 kgs  2.5 Tablet 40 kgs  40 Tablet
45 kgs 11 Tablets 45 kgs 3 Tablet 45 kgs 45 Tablet